Stadt Köln nimmt geplante Kita-Schließung nach Protesten zurück
Der Protest für den Erhalt der (Uni-)Kita Weyertal, zu dem wir auch beigetragen haben, war erfolgreich! Die Kita bleibt.
Allgemein
Mental health in times of crisis
Today we would like to draw your attention to an exciting event that we, the Physics Ombudspersons, have organized for you with the support of the SFBs 1238 and 1601, the TRR 183, and the Cluster of Excellence ML4Q; a talk and workshop on „Mental health in times of crisis“ taking place on 24.01.2024.
We live in times when the framework in which we move safely and comfortably because we are familiar with it, is no longer as tight as we were used to for a long time. Crises, or events perceived as crises, influence our daily lives and can make us feel overwhelmed, powerless, and helpless. There seem to be numerous events that can have a lasting impact on our everyday lives, be it climate change, various wars and conflicts, (post-)pandemic transformations, and many other global happenings and human-caused disasters. …
GPK: Lipid nanoparticles – a soft matter perspective on programmable nucleic acid carriers
Tuesday, 23rd of January, 16.00
(16.00 Coffee & Cake in the foyer, 16.30 talk & discussion)
Lecture Hall III
Lipid Nanoparticles represent the most advanced technology for delivery of nucleic acid. The particles exhibit a well-designed core-shell structure containing ordered lipid mesophases that encapsulate nucleic acid. We discuss distinct pH dependent structural transitions in bulk phases of cationic ionizable lipids and their role in nucleic acid transfer.
These structural transitions are related to gene delivery activity. We show that understanding the content and release kinetics of lipid nanoparticles that contain multiple nucleic acid species, allows for the design of regulatory motives, e.g. feed forward loops, resulting in tailored expression kinetics.